Model organisms are species that researchers use to study specific biological processes. Model organisms provide valuable insights into biological systems at the cell, tissue, organ and system levels. They have similar genetic characteristics to human beings and are often used in the research fields of genetics, developmental biology and neuroscience. Model organisms are usually selected because they are easy to maintain and reproduce in a laboratory environment, have a short generation cycle, or can produce mutants to study certain traits or diseases.
Creative BioMart has established a model organism development platform that adaptive to optogenetic research. Through the platform, model organism gene editing, animal management and model organism development can be achieved.
It integrates gene editing, strain customization, model establishment, germplasm conservation and product development, and can provide gene editing services from cell lines to whole animals. Based on highly educated talents, with industry-leading R&D technology and world-class facilities and equipment, the platform has formed unique advantages in the field of gene editing R&D and reached the international advanced level. So far, the platform has successfully developed thousands of gene editing mice and rats, including systemic knockout, conditional knockout, transgenic, fixed-point knockin and other types. It has provided a large number of gene editing animals for scientific research institutes at home and abroad. At present, it is also committed to the research and development of zebrafish, fruit fly, Caenorhabditis elegans, toad and other model organisms.
Animal management is a comprehensive management platform integrating animal feeding, testing, supply, experimental skill training and other functions to realize scientific and standardized animal experiments. The platform management area includes rats and mice, zebrafish, fruit flies, Caenorhabditis elegans, toads and other experimental animals. The platform manages experimental animals in strict accordance with the specified standardized operation process, and professional inspectors regularly monitor and maintain the feeding environment, so as to ensure the growth of experimental animals in a scientific and standardized feeding environment, provide guarantee for the health of experimental animals and the standardization of experimental operation, so as to successfully complete the experiment and ensure the authenticity and reliability of experimental data.
The platform aims to provide high-level animal experiment support for basic medical research and drug research and development based on optogenetics. After years of development, the platform has a professional animal experiment technology team and perfect animal experiment infrastructure. It can use rats and mice and other animals to build models for heart, nervous system, behavior, hearing, vascular development and optogenetics research. The platform also has the functions of new technology development, animal imaging examination and physiological and biochemical detection. The platform has established a variety of stable and reliable animal models of human diseases, such as epilepsy, pain, diabetes, retinal grade, and kidney injury. At the same time, the platform has also established the phenotypic evaluation system and animal physiological and biochemical detection system of various models, which can provide stable and reliable research data.
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