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Optogenetic is a technology involving the use of light to manipulate cell activities with high temporal and spatial accuracy in vitro or in vivo. The activity of selected cells can be turned on and off on a biologically relevant time scale of a few milliseconds. The field of optogenetics integrates optics and genetic engineering to measure and manipulate cells (usually neurons) and corresponding molecular processes. Compared with drugs and lesions, optogenetic has much higher specificity and control over single cells.
As a leading enterprise in the field of life sciences, Creative BioMart has been committed to continuously developing and improving our optogenetics platform. The related services of mammals, bacteria, yeast, insects, plant cells and even acellular systems have been classified in other pages according to the type of cell. Here we provide some links you may be interested in.
The silencing service is generally applicable to cardiomyocytes and different types of neurons in mice and zebrafish. Explore the role of a single neuron in controlling network activity and behavior. To study the effect of local heart block area.
Experimental design often requires rich experience, and any incomplete consideration will lead to the failure of the experiment. When designing photogenetics experiments, opsin and delivery system need to be selected at the same time. The factors we will consider include but are not limited to excitation or inhibition, activates the color of the light, stimulation time and opsin delivery system.
Viruses are ideal vectors for transgene transmission because they naturally penetrate into host cells and effectively use natural transcription mechanisms to drive the expression of viral genes. Here, we provide the viruses most commonly used in optogenetic research, including lentivirus, adeno-associated virus (AAV), canine adenovirus, herpes simplex virus and rabies virus.
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