C. Elegans Knock-out Services
Gene knockout is the basis of reverse genetics. They allow researchers to study the effects of the deletion of specific genes, protein fragments, amino acids or regulatory elements, so that researchers can determine their function. Gene knockout is a common tool for biologists to understand gene function. When genes are deleted, examining phenotypes can reveal the role of genes in organisms.
Creative BioMart provides full gene deletion, partial gene deletion, conditional gene deletion services.
C. elegans Full Gene Deletion Service
We can use CRISPR / cas9 to delete the entire coding sequence of the gene. Then, you can study the phenotype of truly ineffective alleles without worrying that any protein function still exists. Our transgenic designers and processes ensure that every gene knockout we make is the right strain to answer research questions.
C. elegans Partial Gene Deletion Service
The precision deletion service uses CRISPR / cas9 genome editing to delete a small DNA defined region. This is useful for deleting protein domains, DNA regulatory regions, or any other sequence of your choice.
C. elegans Conditional Gene Deletion Service
Floxed alleles can be created for tissue or time-specific deletions of genes of interest to you. This is a powerful tool for studying embryonic lethal genes or understanding how genes of interest to you play a role in different tissues. CRISPR / cas9 is used to insert loxP sites on both sides of the region to be deleted.
Service Package
You provide the gene editing idea and we expertly design and deliver your transgenic animals within a few months.
| Service Package |
Description |
| One-stop strain construction service |
Provide your idea of gene editing, we will professionally design and deliver your transgenic animals within a few months. |
| Candidate Lines |
A budget friendly alternative to one-stop service. The candidate line service provides animals that have passed our first round of screening and are likely to carry the gene editing you want. |
| Custom Injection Mix |
You provide the idea of gene editing, and we provide you with professionally designed reagents to start your transgenic project. |
Creative BioMart's Service Process
We can screen the drug and / or compound libraries available on the market to reveal the drugs most suitable for the treatment of rare genetic diseases.
Understand your goals. We will have a communication with you to understand your needs. In this call, we will define your project scope, answer your practical questions and help you evaluate whether our services are suitable for you.
Create a personalized catalog. After we decide on the scope of the project, we will create a proposal, including an estimate of the cost and time of each proposed experiment. You will be able to personalize your project plan.
Complete your project design. We will send you the final statement of work and payment schedule. After receiving your first requirement, we will start the experiment and provide a clear timetable for your project.
Keep it clear and transparent. We will inform you of your project status every two weeks. At the end of your project, we will provide you with a report, including comprehensive findings and key points.
Creative BioMart is always devote us to provide high-quality and satisfactory service to our customers, if you are interested in our services or have some question, please feel free to contact us or make online inquiry.
