Light Control Insect System

Creative BioMart provides Drosophila S2 cell line construction services and Semliki Forest virus vector construction services for locusts. As an unparalleled global supplier of life science services and products, we have been committed to providing our customers with comprehensive services from vector construction to target protein synthesis.

Drosophila Schneider 2 (S2) Cell Line for Optogenetic Research

Light Control Insect System

Drosophila Schneider 2 (S2) cells have long been considered as a powerful cell culture model to study the potential mechanism of controlling cell division. The study of these very dynamic cellular processes needs to develop from established genetic methods to methods with high spatial and temporal control to disrupt protein function. The progress of optogenetic tools for rapidly regulating protein activity with light provides unprecedented spatio-temporal control for dynamic cellular processes, and may bring fruitful results to cell biologists.

Semliki Forest Viral Vector for Optogenetic Research

Light Control Insect System

Locust is a widely used animal model to study sensory processing and its relationship with behavior. Locust is a popular model to study behavior dependent on visual movement, especially visual induced escape and collision avoidance behavior. It is desirable to create transgenic locust strains or develop effective transfection methods in locusts to provide neuronal activity indicators or regulators to improve the ability of the model system. Photogenetics is an effective stimulation method, and optical gated ion channels (such as rhodopsin, halorhodopsin and their variants) can be used to control neuronal activity.

Services and Core Facilities

  • Stereomicroscope, external light source and humidifying CO2 system for anesthetizing insects.
  • Fluorescence sorting stereo microscope / imaging video imaging equipment for behavior analysis
  • A kitchen for preparing food and a refrigerator for storing food vials.
  • Isolation room for fly wire and infection testing from outside the facility. The quarantine room has two microscopes with carbon dioxide system.
  • Humidity and light controlled insect incubator at different temperatures.
  • Cell culture biosafety cabinet
  • Cell incubator
  • Plastic products and consumables for cell culture

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