The analysis of complex neural networks usually depends on interfering with the activity of a single gene product, pharmacologically disturbing neuronal activity or damaging specific brain regions to study the response of networks in behavioral output. However, in vitro experiments cannot examine the function of specific cells or cell types in a space or time limited environment.
Recent advances in the field of optogenetics now enable researchers to monitor and manipulate the activities of gene defined cell populations with the unique speed and accuracy of light. Transgenic mice are designed to express photogenetic tools in a cell type specific manner, providing a powerful way to examine the role of specific cells in discrete circuits in a defined and repeatable manner. In recent years, a variety of mouse strains have been developed for optogenetic research.
At present, Creative BioMart has developed a variety of mouse strains expressing Channelrhodopsin, halorhodopsin and Archaerhodopsin respectively, which facilities the application of optogenetic. We have complete animal maintenance facilities to ensure animal health and animal welfare.
| Germ-Free Mouse Facility | Highly-cleaning Facility | Standard Environment |
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Creative BioMart is always devote us to provide high-quality and satisfactory service to our customers, if you are interested in our services or have some question, please feel free to contact us or make online inquiry.
