Microalgae, also known as micro cells, are multi lineage groups from prokaryotes to eukaryotes. Microalgae have complex optical sensing systems, including photoreceptors and optical modulation signal pathways, to sense environmental information and ensure survival in a rapidly changing environment.
The production of valuable compounds by recombinant algae has led to promising biotechnology applications. In microalgae expression system, some viral components are used for innovative genetic engineering methods. Marine microalgae Schizochytrium sp. is an attractive species. It can grow heterotrophically in seawater without relying on photobioreactor.
Creative BioMart provides Schizochytrium sp. based photogenetics platform construction services and protein expression services. Combined with the optimized expression conditions, we can provide high-yield recombinant protein in the shortest time and provide customers with satisfactory experimental results.
As eukaryotes, algae can undergo post-translational modifications (such as glycosylation), which are usually necessary for protein function.
In the production of recombinant protein, microalgae are non-toxic and non animal, which makes microalgae have advantages in biosafety.
Algae are becoming more and more attractive in biopharmaceutical production through post-translational modification and reducing the pollution of pathogenic compounds.
After years of development, some algae have been used as model organisms for photosynthesis, plant biology and lipid metabolism. They can also be used as the basis of biological production platforms for biofuels, nutrients and special chemicals.
We had optimized a green light regulated Synechocystis sp. gene expression system, which can be used for the engineering production of biomaterials and biofuels. Under green light illumination, the constructed engineering green light sensing system has about 30 times higher protein expression than the wild-type promoter with high on / off ratio.
improved a green light regulated T7 RNA polymerase expression system and introduced it into Synechocytis sp. PCC6803, which provides a new and multifunctional high expression system for cyanobacteria, and realizes gene expression in Cyanobacteria with high expression level without using any chemical inducer.
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